Surface Markers Guide the Journey toward Naive Pluripotency
نویسندگان
چکیده
منابع مشابه
YAP Induces Human Naive Pluripotency
The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage of development, has been difficult to capture and sustain in vitro. We report that the Hippo pathway effector YAP is nuclearly localized in the inner cell mass of human blastocysts. Overexpression of YAP in human embryonic stem cells (ESCs) and induced PSCs (iPSCs) promotes the generation of naive PSCs....
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BACKGROUND Adenomyosis is a proliferative uterine dysfunction with unknown aetiology. One possible mechanism of its development involves disturbances in stem cell differentiation in uterine tissue. Previously, we identified pluripotent/multipotent cells in the bovine uterus, therefore our present study focused on determining expression of pluripotency markers, NANOG, OCT4 and SOX2, in bovine ad...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2017
ISSN: 1934-5909
DOI: 10.1016/j.stem.2017.05.004